
**************************************************************************************************** ******************************************************************************************** 1.Study # C12-D036 Facial Acne Study: 6 Visits/ 8 Weeks/ Pays $230.00 EXCLUSIVE STUDY: Cannot be on any other study, and there is a 4 week break between any other study of any kind. TEST PRODUCT: Topical Facial Cleanser/Acne Treatment Product >>>MUST HAVE THE FOLLOWING TO QUALIFY<<< 1. Males and Females. 2. AGE: 25+ 3. MUST HAVE: 5+ Acne Bumps 4. MUST HAVE: 5+ Clogged Pores 5. MUST HAVE: Marks ( on both sides of the cheeks ) from where acne healed. 6. Have not participated in any other study of any kind 4 weeks prior to visit one. 7. Willing to give up your face lotion at least 3 days prior to visit one. DESCRIPTION of STUDY***Please READ*** Visit 1: Subjects arrive at the clinic having washed their faces and removed all eye makeup at least 2 Hours prior. They will complete normal paperwork, have their faces examined for the presence of at least 5 inflammatory acne lesions and 5 non-inflammatory lesions as well as 2-3 PIH marks on each side of the face. Subjects who DQ by exam or because the study is full will be mailed a DQ check. Qualified subjects will enrolled in the study, have lesion counts and digital photos taken, receive their test product, usage instructions, a daily diary, and a calendar of future visits. Subjects will apply the product while at the clinic. Visits 2 - 6: Subjects return to the clinic for repeat facial grading/lesion counts, and complete a questionnaire. Photos will not be repeated. NOTE: You need to bring you NON-MEDICATED bar of soap with you to visit one. (anything medicated for acne will DQ you) VISITS: 6 Visits/ 8 Weeks/ Pays $230.00 EXCLUSIVE STUDY: Group 2: V1: Wed. 2/22/12 3:30 to 6:30 ( up to 1.5 hrs ) V2: Thurs. 2/23/12 4:30 to 6:00 ( up to 45 min ) V3: Fri. 2/24/12 4:30 to 6:00 ( up to 45 min ) V4: Wed. 2/29/12 4:30 to 6:00 ( up to 45 min ) V5: Wed. 3/21/12 4:30 to 6:00 ( up to 45 min ) V6: Wed. 4/18/12 4:30 to 6:00 ( up to 45 min) PAYDAY $230.00 Group 3: V1: Tues. 2/28/12 3:30 to 6:30 (up to 1.5 hrs ) V2: Wed. 2/29/12 4:30 to 6:00 ( up to 45 min ) V3: Thurs.3/01/12 4:30 to 6:00 ( up to 45 min ) V4: Tues.3/06/12 4:30 to 6:00 ( up to 45 min ) V5: Tues. 3/27/12 4:30 to 6:00 ( up to 45 min ) V6: Mon. 4/23/12 4:30 to 6:00 ( up to 45 min ) PAYDAY $230.00 Please, answer and return the study questions to: ginarobinson5392@gmail.com 1. Your name? 2. Your telephone number? 3. Your age? ( 25+) 4. Do you have 5+ Facial Acne Bumps+ 5. Do you have 5+ Facial Clogged Pores? 6. Do you have some spots left over on the face where acne has healed? ( They look like darkened spots) 7. Are on currently on any other study? 8. Will it be at least 4 weeks since the completion of any other study by visit one? 9. Is your face and eyes free from any infections or rashes such as rosacea, psoriasis, eczema, or keratosis? 10.Have you used any Rx or OTC topical medications and/or soaps/makeups that contain topical medications (including anti-acne or antibacterial agents, topical anti-inflammatories, topical retinoids, etc.) within a two (2) week period before the start of the study. 11. What is the name of the bar of soap you will bring to visit one that you use to clean your face? ( MUST BE NON-MEDICATED ) 12. Have you been diagnosed with known allergies to any personal care products, including acne products or their ingredients (i.e. salicylic acid, benzoyl peroxide, witch hazel, fragrance, copper, preservatives, alcohol, zinc, etc.)? 13. Males: Do you have facial hair? 14. Females: Are you pregnant, nursing or trying to become pregnant during this study? 15. Do you have any uncontrolled disease such as diabetes, hypertension, hyperthyroidism, hypothyroidism, or hypercholesteremia? ( Individuals having multiple health conditions may be excluded from participation even if the conditions are controlled by diet, medication, etc). 16. Males: Are you using testosterone supplementation? 17. Females: If you are on hormones for at least the last 3 months, stay on them and if you are not on hormones, please do not start them. Is that OKAY with you? 18. Have you used any oral medication within 30 days or topical medication within 14 days prior to study entry, which could interfere with the outcome of the study. This includes such therapies as the following: certain antibiotics to treat acne (e.g., tetracycline and similar compounds, minocycline, doxycycline, clindamycin), anti-inflammatory drugs such as systemic corticosteroids and topical steroids on the face ****19.Are you willing to use your regular brand of non-medicated facial moisturizer (basic cream) regularly for at least 2 weeks prior to the screening/baseline visit, and then discontinue use of basic cream for 3 days prior to the screening/baseline visit and for the remainder of the study. 20. Are you willing to avoid the sun while on this study? 21. Females: Are you willing to remove your make-up before all visits? 22. Do you know where the Stephens Clinic is? 23. Do you have any friend who might want to do this study? If so, may I have a name and a number? 24. What group? What time? Gr. 2: Wed. 02/22/12 between 3;30 pm - 6:30 pm Gr. 3: Tues. 02/28/12 between 3;30 pm - 6:30 pm Please make sure you can and will be able to make all visits. ************************************************************************************************ 3. Study # C12-D035 Face Lotion Study: 4 Visits/ 8 Weeks/ Pays $150.00 TEST PRODUCT: Face Lotion >>>MUST HAVE THE FOLLOWING TO QUALIFY<<< 1. Age –35 to 55. 2. Females Only 3. Asian and Hispanic (all other groups are full.) 4. In General Good Health 5. Have Had at least a 4 week break since the completion of a face usage study. 6. MUST HAVE: Mild to moderate dark spots/age spots AND uneven skin tone. 7. MUST HAVE: At least 1 of the following: sun damage, hyperpigmentation, and/or acne marks ( dark spots left over from acne) >>>DESCRIPTION OF STUDY****PLEASE, READ***** Visit 1: Subjects report to the clinic having removed ALL facial makeup at least 20 minutes prior to their scheduled appointment. Subjects will have facial examinations for the presence of mild to moderate dark spots/age spots AND uneven skin tone as well as 1 of the following: sun damage, hyperpigmentation, and/or acne marks (PIH/PIE). Please , be aware that this is a screening visit, and if you DQ by exam or because the study has filled, you will be mailed a $10 DQ check. Qualified subjects will complete normal paperwork, (a subgroup will have Corneometer measurements taken on their forearms), all subjects will apply the product while in the clinic, have repeat facial grading, and complete a questionnaire (Subjects in the subgroup will Corneometer measurements repeated). They will receive product usage instructions, a daily diary, and a calendar of study visits. Visits 2 - 4: Subjects return to the clinic for repeat facial grading and questionnaires NOTE: There is a 3 DAY washout from all lotions to the forearms. VISITS: 4 Visits/ 8 Weeks/ Pays $150.00 Group 5:
Visit 1: Fri. 02/24/12 9:30 to 1:00pm ( up to 2 hours )
Visit 2: Fri. 03/02/12 10:30 to 1:00pm ( up to 1 hr )
Visit 3: Fri. 03/23/12 10:30 to 1:00pm ( up to 1 hr ) Visit 4: Fri. 04/20/12 10:30 to 1:00pm (up to 1 hr )PAYDAY $150.00Please, answer and return the study questions to: This takes about 2 minutes ginarobinson5391@gmail.com 1. Your name? 2. Your telephone number? 3. Your age? ( 35 - 55 ) 4. Your ethnicity? ( all other groups are full ) Asian Hispanic 5. Which of the following do you have on the face? Sun-damaged skin Uneven skin tones Dark Spots Spots left over from acne 6. Do you have facial dark spots/age spots? 7. Are you currently on any other Usage Study? 8. Have you had at least 4 weeks since the completion of any other Face Usage Study? 9. Do you have any eye infections or facial rashes such as Eczema, Rosacea? 10. Are your forearms free of cuts, scraps, wounds, sunburn or rashes? 11. Are you willing to NOT use any lotion on the forearms 3 DAYS prior to visit one? 12. Are you pregnant, nursing, or planning to become pregnant within the next six months? 13. Do you have any known allergies to skin care products? 14. Do you have any Uncontrolled metabolic diseases such as diabetes, hypertension, hyperthyroidism, or hypothyroidism or active hepatitis, immune deficiency (such as HIV), or autoimmune disease? 15. Are you using any of the following products?
16. Are you willing to avoid the sun to the face and forearms while on this study? 17. Are you willing to remove ALL make-up before each visit? 18. If you are on hormones please STAY on them, and if you are not on hormones, please DO NOT start them. Is that OKAY with you? 19. Do you know where the Stephens Clinic is? 20 What time? (remember, no lotion on the forearms 3 days prior to visit one) Gr. 5: Fri. 02/24/12 between 9:30am - 1:00pm ( 2 hr s) *************************************************************************************************** 3. Study # C11-D251 Anti-Aging Face Usage Study: 6 Visits/ 16 Weeks/ PAYS $250.00 EXCLUSIVE STUDY: Cannot do any other study while on this study. NOTE: This study is looking for PAIRS of sisters that are within 5 years of each other. However, if you do not have a sister, you can still do this study. TEST PRODUCTS: Anti-Aging Night Cream with Day Cream or Face Serum >>>MUST HAVE THE FOLLOWING TO QUALIFY<<< 1. Very Fair, Fair, Medium or Tan Females 2, Age 35 to 60. 3.General Good Health 4. Very Fair, Fair, Medium or Tan skin tones only 5.DO NOT routinely use facial skin care regimen.) (use cleanser and cosmetics only.) 6.Had at least a 4 week break since previous participation in any other facial usage study. 7. MUST HAVE THE FOLLOWING
8. If possible, pairs if sisters no more than 5 years apart who can do this study together. Description of Study***PLEASE READ*** Visit 1 (Screening): Prospective subjects for come to the clinic to be screened for the presence of mild to moderate overall facial photoaging, mild to moderate forehead wrinkles, and mild to moderate wrinkles in the crow’s feet area. Subjects must have removed all make-up at least 30 minutes (and maximum of 2 hours) before coming to the clinic. Subjects need to understand that this is a screening visit and they may not qualify either by exam or because the study is full. Subjects that do not qualify will be mailed a check for $15.00. Qualified subjects will complete normal paperwork, have facial grading including pinch recoil, digital photos, SKICON and TEWL measurements. Silicone replicas will be taken of either the crow’s feet area or the forehead, and complete a self-assessment questionnaire, Subjects will be given their test products (Anti-Aging night cream, day cream, or serum), usage instructions, a daily diary and a calendar of future visits. Visits 2 - 6 Subjects return to the clinic for repeat facial examinations and questionnaires. Photos will be repeated at Visit 3-6. SKICON and TEWL measurements will be repeated at Visits 2, 3, and 6. Silicon replicas will be repeated at Visits 3, 5 and 6. VISITS: 6 Visits/ 16 Weeks/ Pays $250.00 EXCLUSIVE STUDY Group 4:
Visit 1: Thurs. 03/01/12 10:00am to 1:00pm ( up to 2.5 hrs) Visit 2: Thurs. 03/15/12 11:00am to 1:00pm ( up to 1 hr ) Visit 3: Thurs. 03/29/12 11:00am to 1:00pm ( up to 1 hr ) Visit 4: Thurs. 04/26/12 11:00am to 1:00pm ( up to 1 hr ) Visit 5: Thurs. 05/24/12 11:00am to 1:00pm ( up to 1 hr ) PAYDAY $250.00 Here are the study questions. They take about 2 minutes to answer. Please, return them back to: ginarobinson5391@gmail.com 1. Your name? 2. Your telephone number? 3. Your age? ( 35 - 60 ) 4. Do you have a sister within 5 years of your age that could do this study with you? If so, can she please answer and return these study questions, or may I have a name and a number? 5. What is your skin tone? Very Fair Fair Medium Tan Dark Very Dark 6. Do you have ALL of the following?
7. If your sister will also be attending this study, does she have all of the above in question 6? 8. Are you currently on any other study? 9. Has it been at least 4 weeks since the completion of any other Face Usage Study? 10. Do you have any disease or condition of the skin that would make it inappropriate for you to participate? 11. Do you have any known allergies or sensitivities to cosmetic products, toiletries or their components or ingredients in the test products (fragrances, preservatives, Vitamin C, Retinol, AHAs, soy, dioic acid, etc.)? 12. Are you pregnant, nursing or trying to become pregnant? 13. Do you have any active hepatitis, immune deficiency (such as HIV), or autoimmune disease OR Atopic dermatitis, eczema, psoriasis, seborrheic dermatitis, acne or rosacea on the face? 14. Have you had any facial cosmetic surgery, fillers, Botox or peels in the last 6 months? 15. Can you avoid the sun while on this study? 16. Have you routinely used topical prescription or OTC facial treatment products containing alpha-, beta- or poly-hydroxyacid (including salicylic acid and Lachydrin), retinol or derivatives of retinol or other ‘anti-aging’ products on the face within 30 days of the study start. 17. If you are on hormones, please stay on them, if you are not hormones please do not start them while on this study. Is that okay with you? 18. Can you remove ALL make-up before each visit? 19. Do you know where the Stephens Clinic is? 20. What time? Gr. 4: Fri. 03/01/12 between 10:00am - 1:00 pm ( up to 2.5 hrs ) 4. Study # C12-D043 SPF Retinol Study: 4 Visits/ 8 Weeks/ Pays $140.00 EXCLUSIVE STUDY: Cannot be on any other study of any kind. TEST PRODUCT: SPF Retinol Serum Study >>>MUST HAVE THE FOLLOWING TO QUALIFY<<< 1. FEMALES: who are Very Fair, Fair, Medium, or Tan 2. AGE: 35 - 55 3. Need to be in good health 4. MUST HAVE: Fine and moderate facial wrinkles 5. There is a 1- 3 day washout from facial moisturizers, sunscreens or hydrating products. Description of Study***Please, READ*** Visit 1: Subjects report to the clinic having removed all facial makeup at least 20 minutes prior to their scheduled appointment. They will complete normal paperwork and have their faces examined for the presence of fine AND moderate wrinkles. Subjects need to understand that this is a screening visit, and if they are DQ’d by exam or because the study has filled, they will be mailed a DQ check. Qualified subjects will have Corneometer measurements taken as well as photos. They will receive their test product, usage instructions, a daily diary and a calendar of future visits, and they will apply the product under clinic supervision. Visits 2 - 4:
Subjects return to the clinic for repeat facial examinations, Corneometer measurements, and self-assessment questionnaires. Photos will be repeated at Visit 4 only. VISITS: 4 Visits/ 8 Weeks/ Pays $140.00 EXCLUSIVE STUDY Visit 1: Thurs. 2/23/12 11:00 to 1:00pm ( up 1.5 hours ) Visit 2: Thurs. 3/08/12 12:00 to 1:00pm ( up to 30 min ) Visit 3: Thurs. 3/22/12 12:00 to 1:00pm ( up to 30 min ) Visit 4: Mon. 4/19/12 12:00 to 1:00pm ( up to 45 min ) PAYDAY $140.00 Please, answer and return the study questions to: ginarobinson5391@gmail.com 1. Your name? 2. Your telephone number? 3. Your age? ( 35 - 55 ) 4. Your ethnicity? 5. Your skin tone? Very Fair Fair Medium Tan Dark Very Dark 6. Are you currently on or scheduled to start another study? 7. Has it been at least 4 weeks ( 28 days ) since the completion of any other study, prior to visit one? 8. Do you have fine lines and facial wrinkles? 9. Are you pregnant/nursing or trying to become pregnant? 10. Have you been diagnosed with or have any known allergies or sensitivities to facial skin care products? 11. Do you have any eye infections of facial rashes such as psoriasis, rosacea, atopic dermatitis, moderate to severe acne, eczema, seborrheic dermatitis, or severe itchy facial skin? 12. Do you have a History of immunosuppression/immune deficiency disorders (including (HIV infection or AIDS) or currently using immunosuppressive medications? 13. Do you have any uncontrolled disease such as diabetes, hypertension, hyperthyroidism, or hypothyroidism? ( Individuals having multiple health conditions may be excluded from participation even if the conditions are controlled by diet, medication, etc.) 14. Have you used any anti-aging, anti-wrinkle products, antioxidants or skin lightening products within 30 days of visit one? 15. Have you had any facial procedures done in the last 12 months? ( Botox, Laser, Chemical Peel, face lift, eye lift etc... ) 16. Are you sure that you can make all visits in the group that you choose? 17. Do you know where the Stephens Clinic is? 18. What time?
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